Blood leucocyte telomere DNA content predicts vascular telomere DNA content in humans with and without vascular disease

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Blood leucocyte telomere DNA content predicts vascular telomere DNA content in humans with and without vascular disease.

AIMS Previous studies have suggested that reduced telomere length in circulating leucocytes in humans is associated with premature vascular disease and by implication, accelerated vascular ageing. Importantly, a link between telomere length in circulating leucocytes and the blood vessel wall has never been established. We, thus, investigated the relationship between vascular wall and circulatin...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2008

ISSN: 0195-668X,1522-9645

DOI: 10.1093/eurheartj/ehn386